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Hypercholesterolemia
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Hypercholesterolemia, or high
cholesterol, is a high level of cholesterol in the blood that
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can leads to blockages in the arteries , increasing the risk for heart
attack, |
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stroke and circulation problems. |
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What Is Cholesterol? |
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Cholesterol is a soft, waxy fat
particle that circulates in the blood. It has several
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important functions in the body: it is
a building block for all cell membranes
and many |
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sex hormones & steroid hormones,
and is the digestive substance released by the gall |
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bladder. |
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The body produces cholesterol in the
liver. The liver, in fact, produces almost all of the
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cholesterol the body needs. However, many popular foods contain
cholesterol and the |
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substances used to produce cholesterol
particles, which can increase the amount of |
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cholesterol in the blood. Being
insoluble in blood, cholesterol is circulated around the |
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body with the help of
protein carriers called lipoproteins. |
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Two of these protein
carriers are low-density lipoproteins (LDL) "bad cholesterol"
& high- |
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density lipoproteins (HDL) "good cholesterol”.
Lipoproteins are differentiated according to |
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the degree of density. |
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LDL is responsible for transporting
cholesterol from the liver to various tissues & body |
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cells while HDL basically delivers any excess or unused cholesterol
back to the liver to |
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have it broken down to bile acids for
excretion. |
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Risk factors |
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Specific risk
factors include a family history of high cholesterol, obesity,
heart attack or |
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stroke,
alcoholism, and lack of regular exercise.
The chances of developing high |
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cholesterol
increase after the age of 45. One of the primary causes of high LDL |
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cholesterol is too much fat or sugar in the diet.
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Causes & symptoms |
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There
are no apparent symptoms that indicate high LDL or
triglycerides, or low HDL. |
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The only way to
diagnose the problems is
through a simple blood test. |
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However, one
general indication of high cholesterol is obesity. |
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Diagnosis |
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To diagnose
hypercholesterolemia different tests like Total
cholesterol, LDL, HDL, and |
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triglyceride
levels as well as thecholesterol to HDL
ratio are performed. . The results |
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should only be
used as a guide and if the total cholesterol level is high or low, a |
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complete lipid
will give proper information. |
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In most adults the recommended levels,
measured by milligrams per deciliter (mg/dL) of |
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blood, are: total cholesterol, less than 200; LDL,
less than 130; HDL, more than 35; |
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triglycerides, 30-200; and cholesterol
to HDL ratio, four to one. |
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However, the recommended cholesterol
levels may vary, depending on other risk factors |
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such as hypertension, a familyhistory of heart
disease, diabetes, age, alcoholism, and |
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smoking. |
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Control
of hypercholesterolemia |
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Since a large
number of people with high cholesterol are overweight, a healthy
diet and |
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regular exercise
are most beneficial
natural ways to control cholesterol levels. |
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Weight loss.
Gradual weight loss through modified diet and
increased physical activity is |
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helpful. |
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Physical activity.
Regular, moderate aerobic exercise has many beneficial effects.
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Exercise
such as taking a brisk, 20-30 minute walk, 3-5 times
in a week. |
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All persons with
chest pain (angina) and known or
suspected heart disease should take
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physician advice before following
any plan. |
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Treatment |
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The primary
goal of cholesterol treatment is to lower LDL to under 160
mg/dL in people without heart disease and who are at lower
risk of developing it. The goal in people with higher risk
factors for heart disease is less than 130 mg/dL. In patients
who already have heart disease, the goal is under 100 mg/dL,
according to FDA guidelines. Also, since low HDL levels
increase the risks of heart disease, the goal of all patients
is more than 35 mg/dL. |
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In both alternative and
conventional treatment of high cholesterol, the first-line
treatment options are exercise, diet, weight loss, and stopping
smoking. Other alternative treatments include high doses of
niacin, soy protein, garlic. |
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